The tissue adhesive Histoacryl® consists of monomeric n-butyl-2-cyanoacrylate, which polymerises quickly in connection with tissue fluid. Histoacryl® is available in two colours: translucent, special for facial application, and blue, which enables an easy control over the quantity applied in different indications approved.
Advantages
Skin closure
- Wound closure in one minute [1, 2, 3, 4]
- Significant less pain than suture materials [5]
- Effective microbial barrier [6, 7, 8]
- Storage at room temperature <22º [9]
- High level of patient and physician satisfaction [2, 7, 10, 11, 12]
- Save time and costs [1, 2, 3, 4, 5, 10, 12]
- Only one layer is needed [4, 8]
- Histoacryl® can be used for closure of endoscopic incisions [8, 13]
Sclerotherapy
- For bleeding and non-bleeding varices [14, 15, 16, 17, 18, 19]
- Combined therapy with Histoacryl® and conventional sclerosation therapy is possible] [14, 15, 17, 20]
- Final hemostasis is achieved in >90% of cases [14, 15, 16, 17, 18, 19]
- Lower rebleeding rate than with band ligation [14, 15, 18, 20]
Mesh fixation
- Non-invasive method reported to be better tolerated by the patient than traditional fixation methods [22, 23, 24, 25, 26]
- Stand-alone fixation method in different hernia repair techniques [22, 23, 24, 25, 26]
- Comparable recurrence rate than with traditional fixation methods [23, 24, 25, 26]
- Low intra- and postoperative morbidity [24, 26]
- Reduced risk of post-operative chronic pain compared to traditional fixation methods [23, 24, 25, 26]
- Decreased surgery time compared to traditional fixation methods [23, 25]
- Good biocompatibility and in vivo tolerance [23, 24, 25, 26, 27]
Indication
- Skin Closure: Closure of skin wounds without tension (including clean surgical incisions and incisions from minimally invasive surgery), and simple, thoroughly cleansed, trauma-induced lacerations.
- Sclerotherapy: Sclerotherapy of large oesophageal or fundal varices.
- Mesh fixation: Fixation of hernia meshes, especially in inguinal hernia surgery.
Reviews
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