BBRAUN Histoacryl® Tissue Adhesive

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The tissue adhesive Histoacryl® consists of monomeric n-butyl-2-cyanoacrylate, which polymerises quickly in connection with tissue fluid. Histoacryl® is available in two colours: translucent, special for facial application, and blue, which enables an easy control over the quantity applied in different indications approved.

Advantages

Skin closure

  • Wound closure in one minute [1, 2, 3, 4]
  • Significant less pain than suture materials [5]
  • Effective microbial barrier [6, 7, 8]
  • Storage at room temperature <22º [9]
  • High level of patient and physician satisfaction [2, 7, 10, 11, 12]
  • Save time and costs [1, 2, 3, 4, 5, 10, 12]
  • Only one layer is needed [4, 8]
  • Histoacryl® can be used for closure of endoscopic incisions [8, 13]

Sclerotherapy

 

  • For bleeding and non-bleeding varices [14, 15, 16, 17, 18, 19]
  • Combined therapy with Histoacryl® and conventional sclerosation therapy is possible] [14, 15, 17, 20]
  • Final hemostasis is achieved in >90% of cases [14, 15, 16, 17, 18, 19]
  • Lower rebleeding rate than with band ligation [14, 15, 18, 20]

Mesh fixation

  • Non-invasive method reported to be better tolerated by the patient than traditional fixation methods [22, 23, 24, 25, 26]
  • Stand-alone fixation method in different hernia repair techniques [22, 23, 24, 25, 26]
  • Comparable recurrence rate than with traditional fixation methods [23, 24, 25, 26]
  • Low intra- and postoperative morbidity [24, 26]
  • Reduced risk of post-operative chronic pain compared to traditional fixation methods [23, 24, 25, 26]
  • Decreased surgery time compared to traditional fixation methods [23, 25]
  • Good biocompatibility and in vivo tolerance [23, 24, 25, 26, 27]

Indication

  • Skin Closure: Closure of skin wounds without tension (including clean surgical incisions and incisions from minimally invasive surgery), and simple, thoroughly cleansed, trauma-induced lacerations.
  • Sclerotherapy: Sclerotherapy of large oesophageal or fundal varices.
  • Mesh fixation: Fixation of hernia meshes, especially in inguinal hernia surgery.

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